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Home Antibody All anti-SHC1 antibodies

Anti-SHC1 PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA312071
  • Rabbit polyclonal Shc (Tyr349) antibody(Phospho-specific)
100ul 325 3 Weeks
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WB(1)
IHC(1)

OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Shc around the phosphorylation site of tyrosine349 (H-Q-YP-Y-N)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~1000, IHC: 1:50~100, ELISA: 1:10000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note Shc (phospho-Tyr349) antibody detects endogenous levels of Shc only when phosphorylated at tyrosine349.

Reference Data

Target NameHomo sapiens SHC (Src homology 2 domain containing) transforming protein 1 (SHC1), transcript variant 1
Alternative NameSHC; SHCA
Database LinkNP_892113
Entrez Gene 6464 Human
Entrez Gene 20416 Mouse
Entrez Gene 85385 Rat
Function
Related PathwayDruggable Genome ErbB signaling pathwayChemokine signaling pathwayFocal adhesionNatural killer cell mediated cytotoxicityNeurotrophin signaling pathwayInsulin signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts from 293 cells treated with EGF (200ng/ml, 30mins), using Shc (phospho-Tyr349) antibody.The lane on the right is treated with the synthesized peptide.
IHC Image
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Shc (phospho-Tyr349) antibodyThe picture on the right is treated with the synthesized peptide.

 

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