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Home Antibody All anti-WASL antibodies

Anti-WASL Antibody EPR6959

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311108
  • Rabbit Monoclonal antibody against N-WASP (WASL)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401293) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
Assay(1)
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Also for WASL (NM_003941)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human N-WASP was used as an immunogen.
Clone NameEPR6959 IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC/IF: 1:50 - 1:100
BufferDoes not react with Rat. Is unsuitable for Flow Cyt or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens Wiskott-Aldrich syndrome-like (WASL)
Alternative NameN-WASP; NWASP
Database LinkNP_003932
FunctionThe Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. N-WASP is a homolog of the WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. N-WASP has been shown to bind Cdc42 directly, and induce formation of long actin microspikes (1).
Related Pathway
Adherens junction
EGFR1 Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-N WASP antibody [EPR6959]; All lanes : Anti-N WASP antibody [EPR6959] at 1/1000 dilution.Lane 1 : NIH 3T3 cell lysate.Lane 2 : F9 cell lysate.Lane 3 : L929 cell lysate.Lane 4 : HeLa cell lysate.Lane 5 : K562 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 55 kDa.
Assay Image
Other-Anti-N WASP antibody [EPR6959](TA311108); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-N WASP antibody [EPR6959]; TA311108, at 1/50, staining N WASP in formalin fixed, paraffin embedded Human papillary carcinoma tissue by Immunohistochemistry

 

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