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Anti-TLR7 Antibody EPR2088(2)
Also for TLR7 (NM_016562)
|A synthetic peptide corresponding to residues on the C-terminus in the intracellular domain of human TLR-7 was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens toll-like receptor 7 (TLR7)|
|TLR-7 is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and they mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR-7 is predominantly expressed in lung, placenta, and spleen (1).|
Toll-like receptor signaling pathway
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Western blot - Anti-TLR7 antibody [EPR2088(2)]; All lanes : Anti-TLR7 antibody [EPR2088(2)] at 1/1000 dilution.Lane 1 : Raji cell lysates.Lane 2 : Ramos cell lysates.Lysates/proteins at 10 µg per lane.Secondary.HRP-conjugated goat anti-rabbit at 1/2000 dilution.Predicted band size : 121 kDa.
Other-Anti-TLR7 antibody [EPR2088(2)](TA311092); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TLR7 antibody [EPR2088(2)]; TA311092, at 1/100 dilution, staining TLR7 in paraffin-embedded Human tonsil tissue by Immunohistochemistry.