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Anti-SRSF1 Antibody EPR8239


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against SF2 (SRSF1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC425877) , 20ug Explanation
100ul $325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SF2 was used as an immunogen.
Clone NameEPR8239 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:250 - 1:500
Predicted MW Explanation 28 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens serine/arginine-rich splicing factor 1 (SRSF1), transcript variant 2
Alternative NameASF; SF2; SF2p33; SFRS1; SRp30a
Database LinkNP_001071634
Entrez Gene 6426 Human
Entrez Gene 110809 Mouse
Entrez Gene 689890 Rat
FunctionSF2 is a member of the arginine/serine-rich splicing factor protein family and functions in both constitutive and alternative pre-mRNA splicing. It binds to pre-mRNA transcripts and components of the spliceosome, and it can either activate or repress splicing depending on the location of the pre-mRNA binding site. SF2's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins (1).
Related PathwayStem cell - Pluripotency Spliceosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-SF2 antibody [EPR8239]; All lanes : Anti-SF2 antibody [EPR8239] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : Raji cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 28 kDa.
Assay Image
Other-Anti-SF2 antibody [EPR8239](TA311077); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SF2 antibody [EPR8239]; TA311077, at 1/100 dilution, staining SF2 in Paraffin-embedded Human breast carcinoma by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-SF2 antibody [EPR8239]; TA311077, at 1/250 dilution, staining SF2 in HepG2 cells by Immunofluorescence.


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