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Home Antibody All anti-SMPD2 antibodies

Anti-SMPD2 Antibody EPR6718

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311073
  • Rabbit Monoclonal antibody against nSMase1 (SMPD2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418911) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IHC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human nSMase1 was used as an immunogen.
Clone NameEPR6718 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsICC/IF: 1:250 - 1:500; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) (SMPD2)
Alternative NameISC1; NSMASE; NSMASE1
Database LinkNP_003071
Entrez Gene 6610 Human
Entrez Gene 20598 Mouse
Entrez Gene 83537 Rat
FunctionnSMase1 was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase (1).
Related PathwayTransmembrane Sphingolipid metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-nSMase antibody [EPR6718]; All lanes : Anti-nSMase antibody [EPR6718] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : MOLT4 cell lysate.Lane 3 : K562 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 48 kDa.
WB Image
Western blot - Anti-nSMase antibody [EPR6718]; All lanes : Anti-nSMase antibody [EPR6718] at 1/1000 dilution.Lane 1 : Mouse brain lysate.Lane 2 : Rat brain lysates .Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 48 kDa.
Assay Image
Other-Anti-nSMase antibody [EPR6718](TA311073); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-nSMase antibody [EPR6718]; Immunofluorescent analysis of U-87 MG cells labelling nSMase with TA311073 at 1/250 dilution.

 

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