Home Antibody All anti-SETD7 antibodies
Anti-SETD7 Antibody EPR5574
Also for SETD7 (NM_030648)
|A synthetic peptide corresponding to residues in human SET7 / SET9 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens SET domain containing (lysine methyltransferase) 7 (SETD7)|
|KMT7; SET7; SET7/9; SET9|
Entrez Gene 80854 Human
Entrez Gene 73251 Mouse
Entrez Gene 689954 Rat
|SET7/ SET9 is a histone methyltransferase that can monomethylate Lysine 4 of histone H3 and regulate protein expression (1, 2). This methylation represents a specific tag for epigenetic transcriptional activation. SET7/ SET9 plays a central role in the activation of proteins such as collagenase or insulin. It is recruited by IPF1/PDX-1 to the insulin promoter, activating transcription. Moreover, SET7/ SET9 has methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins (2).|
|Druggable Genome Lysine degradation|
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Western blot - Anti-SETD7 antibody [EPR5574]; All lanes : Anti-SETD7 antibody [EPR5574] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : BxPC-3 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : MCF-7 cell lysate.Lane 5 : C6 cell lysate.Lane 6 : RAW264.7 cell lysate.Lane 7 : PC-12 cell lysate.Lane 8 : NIH/3T3 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 41 kDa.
Other-Anti-SETD7 antibody [EPR5574](TA311067); Equilibrium disassociation constant (KD)..