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Anti-SETD7 Antibody EPR5574


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against SET7 / SET9 (SETD7)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403067) , 20ug Explanation
100ul $325 3-7 Days
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Also for SETD7 (NM_030648)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SET7 / SET9 was used as an immunogen.
Clone NameEPR5574 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
Predicted MW Explanation 41 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens SET domain containing (lysine methyltransferase) 7 (SETD7)
Alternative NameKMT7; SET7; SET7/9; SET9
Database LinkNP_085151
Entrez Gene 80854 Human
Entrez Gene 73251 Mouse
Entrez Gene 689954 Rat
FunctionSET7/ SET9 is a histone methyltransferase that can monomethylate Lysine 4 of histone H3 and regulate protein expression (1, 2). This methylation represents a specific tag for epigenetic transcriptional activation. SET7/ SET9 plays a central role in the activation of proteins such as collagenase or insulin. It is recruited by IPF1/PDX-1 to the insulin promoter, activating transcription. Moreover, SET7/ SET9 has methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins (2).
Related PathwayDruggable Genome Lysine degradation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-SETD7 antibody [EPR5574]; All lanes : Anti-SETD7 antibody [EPR5574] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : BxPC-3 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : MCF-7 cell lysate.Lane 5 : C6 cell lysate.Lane 6 : RAW264.7 cell lysate.Lane 7 : PC-12 cell lysate.Lane 8 : NIH/3T3 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 41 kDa.
Assay Image
Other-Anti-SETD7 antibody [EPR5574](TA311067); Equilibrium disassociation constant (KD)..


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