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Home Antibody All anti-POLE3 antibodies

Anti-POLE3 Antibody EPR6300

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311032
  • Rabbit Monoclonal antibody against POLE (POLE3)
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for POLE3 (NM_017443)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the C-terminus of human POLE was used as an immunogen.
Clone NameEPR6300 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:1000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens polymerase (DNA directed), epsilon 3, accessory subunit (POLE3), transcript variant 1
Alternative NameCHARAC17; CHRAC17; p17; YBL1
Database LinkNP_059139
FunctionDNA polymerases (pol) play essential roles in chromosomal DNA replication and repair. POLE is a proofreading DNA polymerase, which has been implicated in DNA replication. Moreover, it is associated with origins of DNA replication and it proceeds along the replication fork. In human cells, POLE is associated with actively replicated cellular DNA and has been shown to perform an important fraction of replicative DNA synthesis (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-POLE antibody [EPR6300]; All lanes : Anti-POLE antibody [EPR6300] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : HeLa cell lysate .Lane 3 : 293T cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 262 kDa.
Assay Image
Other-Anti-POLE antibody [EPR6300](TA311032); Equilibrium disassociation constant (KD)..

 

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