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Anti-POLE3 Antibody EPR6300
Also for POLE3 (NM_017443)
|A synthetic peptide corresponding to residues at the C-terminus of human POLE was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:1000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens polymerase (DNA directed), epsilon 3, accessory subunit (POLE3), transcript variant 1|
|CHARAC17; CHRAC17; p17; YBL1|
|DNA polymerases (pol) play essential roles in chromosomal DNA replication and repair. POLE is a proofreading DNA polymerase, which has been implicated in DNA replication. Moreover, it is associated with origins of DNA replication and it proceeds along the replication fork. In human cells, POLE is associated with actively replicated cellular DNA and has been shown to perform an important fraction of replicative DNA synthesis (1). |
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Western blot - Anti-POLE antibody [EPR6300]; All lanes : Anti-POLE antibody [EPR6300] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : HeLa cell lysate .Lane 3 : 293T cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 262 kDa.
Other-Anti-POLE antibody [EPR6300](TA311032); Equilibrium disassociation constant (KD)..