OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-MTDH antibodies

Anti-MTDH Antibody EP4445

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310986
  • Rabbit Monoclonal antibody against Metadherin (MTDH)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403614) , 20ug
100ul $325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(2)
IF(1)
spacer
Also for MTDH (NM_178812)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Metadherin was used as an immunogen.
Clone NameEP4445 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens metadherin (MTDH)
Alternative Name3D3; AEG-1; AEG1; LYRIC; LYRIC/3D3
Database LinkNP_848927
FunctionMetadherin is a potentially crucial mediator of tumor malignancy and a key factor of oncogenic signaling pathways (1). Elevated levels have been observed in some human tumor types, such as breast cancer, prostate cancer, hepatocellular carcinoma, neuroblastoma, esophageal squamous cell carcinoma (ESCC) and non-small cell lung cancer (NSCLC) (2). Metadherin promotes anchorage-independent growth of immortalized melanocytes and astrocytes, which is a key component in tumor cell expansion (3). Several signaling pathways have been found to be associated with the expression of Metadherin, including Ha-ras, PI3K/Akt, NF-?B and Wnt/ß-catenin. (2).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-LYRIC antibody [EP4445]; All lanes : Anti-LYRIC antibody [EP4445] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : PC3 cell lysate.Lane 4 : PC12 cell lysate.Lane 5 : NIH 3T3 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 64 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYRIC antibody [EP4445]; TA310986 at 1/100 dilution staining LYRIC in paraffin-embedded Human brain tissues by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYRIC antibody [EP4445]; TA310986 at 1/100 dilution staining LYRIC in paraffin-embedded Human breast tissues by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-LYRIC antibody [EP4445]; TA310986 at 1/100 dilution staining LYRIC in HeLa cells by Immunofluorescence.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title