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Anti-LEFTY2 Antibody EPR5444


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against Lefty (LEFTY2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC432898) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human Lefty was used as an immunogen. This antibody recognizes Lefty1 and Lefty2.
Clone NameEPR5444 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
Predicted MW Explanation 41 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens left-right determination factor 2 (LEFTY2), transcript variant 2
Alternative NameEBAF; LEFTA; LEFTYA; TGFB4
Database LinkNP_001165896
Entrez Gene 7044 Human
Entrez Gene 320202 Mouse
Entrez Gene 289316 Rat
FunctionLefty is a member of the TGF-beta family of proteins. It is secreted and plays a role in left-right asymmetry determination of organ systems during development. Lefty may also play a role in endometrial bleeding. Mutations in Lefty have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of Lefty in the endometrium (1).
Related PathwaySecreted ProteinDruggable Genome TGF-beta signaling pathway

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Western blot - Anti-LEFTY2 antibody [EPR5444]; All lanes : Anti-LEFTY2 antibody [EPR5444] at 1/10000 dilution.Lane 1 : HeLa cell lysates .Lane 2 : 293T cell lysates .Lane 3 : Caco 2 cell lysates .Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 34,44 kDa .
Other-Anti-LEFTY2 antibody [EPR5444](TA310969); Equilibrium disassociation constant (KD)..


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