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Anti-LEFTY2 Antibody EPR5444
Also for LEFTY2 (NM_001172425)
|A synthetic peptide corresponding to residues on the C-terminus in human Lefty was used as an immunogen. This antibody recognizes Lefty1 and Lefty2.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens left-right determination factor 2 (LEFTY2), transcript variant 2|
|EBAF; LEFTA; LEFTYA; TGFB4|
Entrez Gene 7044 Human
Entrez Gene 320202 Mouse
Entrez Gene 289316 Rat
|Lefty is a member of the TGF-beta family of proteins. It is secreted and plays a role in left-right asymmetry determination of organ systems during development. Lefty may also play a role in endometrial bleeding. Mutations in Lefty have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of Lefty in the endometrium (1). |
|Secreted ProteinDruggable Genome TGF-beta signaling pathway|
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Western blot - Anti-LEFTY2 antibody [EPR5444]; All lanes : Anti-LEFTY2 antibody [EPR5444] at 1/10000 dilution.Lane 1 : HeLa cell lysates .Lane 2 : 293T cell lysates .Lane 3 : Caco 2 cell lysates .Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 34,44 kDa .
Other-Anti-LEFTY2 antibody [EPR5444](TA310969); Equilibrium disassociation constant (KD)..