Home All anti-JAG1 antibodies
Anti-JAG1 Antibody EPR4290
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Also for JAG1 (NM_000214)
|A synthetic peptide corresponding to residues near the C-terminus of human Jagged 1 was used as an immunogen.|
|Human, Mouse, Rat
|WB, IHC, IF
||WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250; IP: 1:10 - 100;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens jagged 1 (JAG1)|
|AGS; AHD; AWS; CD339; HJ1; JAGL1|
|Jagged 1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the Jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoiesis (1). |
Delta-Notch Signaling Pathway
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Western blot analysis on (A) HepG2 and (B) NIH:OVCAR-3 cell lysates using anti-Jagged 1 RabMAb.
Immunohistochemical analysis of paraffin-embedded bladder cancer tissue using anti-Jagged 1 RabMAb.
Immunofluorescent staining of HeLa cells using anti-Jagged 1 RabMAb.