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Home Antibody All anti-WIPI2 antibodies

Anti-WIPI2 Antibody EPR8113

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310940
  • Rabbit Monoclonal antibody against WIPI2
100ul $325 3-7 Days
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WB(1)
IHC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at C-terminus of human WIPI2 was used as an immunogen.
Clone NameEPR8113 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; FC: 1:10 - 1:100
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 3
Alternative NameATG18B; Atg21; CGI-50; WIPI-2
Database LinkNP_001028690
FunctionWIPI2 is a member of the WIPI subfamily of WD40 repeat proteins. It has a 7-bladed propeller structure and contains a conserved motif for interaction with phospholipids (1). WIPI2 is an early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to PtdIns3P. This protein is ubiquitously expressed; Higher expression in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors (2).
Related Pathway

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WB Image
Western blot - Anti-WIPI2 antibody [EPR8113]; All lanes : Anti-WIPI2 antibody [EPR8113] at 1/1000 dilution.Lane 1 : Human placenta tissue lysate.Lane 2 : Human pancreas tissue lysate.Lane 3 : JAR cell lysate.Lane 4 : Human fetal heart tissue lysate .Lane 5 : Saos 2 cell lysate.Lane 6 : BxPC-3 cell lysate.Lane 7 : Caco 2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled Goat anti-Rabbit IgG at 1/2000 dilution.Predicted band size : 49 kDa.
Assay Image
Other-Anti-WIPI2 antibody [EPR8113](TA310940); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-WIPI2 antibody [EPR8113]; Immunohistochemical analysis of paraffin embedded Human skeletal muscle tissue labelling WIPI2 with TA310940 at 1/100 dilution.

 

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