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Anti-USH1C Antibody EPR8131
Also for USH1C (NM_005709)
|A synthetic peptide corresponding to residues in human USH1C was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens Usher syndrome 1C (autosomal recessive, severe) (USH1C), transcript variant 1|
|AIE-75; DFNB18; DFNB18A; NY-CO-37; NY-CO-38; PDZ-45; PDZ-73; PDZ-73/NY-CO-38; PDZ73; PDZD7C;|
|USH1C is a scaffold protein that functions in the assembly of Usher protein complexes. It contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in USH1C are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18 (1).|
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Western blot - Anti-USH1C antibody [EPR8131]; All lanes : Anti-USH1C antibody [EPR8131] at 1/10000 dilution.Lane 1 : Human fetal kidney lysate.Lane 2 : Human colon lysate.Lane 3 : Caco 2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 62 kDa.
Western blot - Anti-USH1C antibody [EPR8131]; All lanes : Anti-USH1C antibody [EPR8131] at 1/2500 dilution.Lane 1 : Squirrel cochlea.Lane 2 : Mouse cochlea.Lane 3 : Squirrel colon.Lane 4 : Mouse colon.Lane 5 : Caco2 cells.Secondary.HRP linked Goat anti-rabbit IgG polyclonal at 1/20000 dilution.developed using the ECL technique.Performed under reducing conditions.Predicted band size : 62 kDa.Additional bands at : 40 kDa (possible isoform),67 kDa (possible isoform).Exposure time : 30 secondsThis image is courtesy of an Abreview submitted by James Bjork
Other-Anti-USH1C antibody [EPR8131](ab133763); Equilibrium disassociation constant (KD)..