Home Antibody All anti-UBE2B antibodies
Anti-UBE2B Antibody EPR7199
Also for UBE2B (NM_003337)
|A synthetic peptide corresponding to residues in human UBE2B was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens ubiquitin-conjugating enzyme E2B (UBE2B)|
|E2-17kDa; HHR6B; HR6B; RAD6B; UBC2|
Entrez Gene 7320 Human
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair (1). |
|Druggable Genome Ubiquitin mediated proteolysis|
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Western blot - Anti-Ube2B antibody [EPR7199]; All lanes : Anti-Ube2B antibody [EPR7199] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : A375 cell lysate.Lane 4 : K-562 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 17 kDa.Observed band size : 17 kDa.
Other-Anti-Ube2B antibody [EPR7199](TA310911); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ube2B antibody [EPR7199]; TA310911, at a 1/100 dilution, staining Ube2B in paraffin embedded Human kidney tissue by Immunohistochemistry.