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Home Antibody All anti-TSG101 antibodies

Anti-TSG101 Antibody EPR7130(B)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310908
  • Rabbit Monoclonal antibody against TSG101
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401898) , 20ug
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for TSG101 (NM_006292)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human TSG101 was used as an immunogen.
Clone NameEPR7130(B) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens tumor susceptibility 101 (TSG101)
Alternative NameTSG10; VPS23
Database LinkNP_006283
FunctionTSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. It contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. TSG101 may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility protein appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations in TSG101 occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-TSG101 antibody [EPR7130(B)]; All lanes : Anti-TSG101 antibody [EPR7130(B)] at 1/1000 dilution.Lane 1 : Human Brain lysate.Lane 2 : K562 lysate.Lane 3 : Jurkat lysate.Lane 4 : SH-SY5Y lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 44 kDa.Observed band size : 45 kDa .
Assay Image
Other-Anti-TSG101 antibody [EPR7130(B)](TA310908); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-TSG101 antibody [EPR7130(B)]; Flow cytometric analysis of permeabilized K562 cells using TA310908 at 1/10 shown in red or a rabbit IgG negative shown in green.

 

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