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Anti-TFPI Antibody EPR7941
Also for TFPI (NM_006287)
|A synthetic peptide corresponding to residues on the C-terminus in human TFPI was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
|Homo sapiens tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (TFPI), transcript variant 1|
|EPI; LACI; TFI; TFPI1|
Entrez Gene 7035 Human
|TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. It is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins (1).|
|Secreted Protein Complement and coagulation cascades|
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Western blot - Anti-TFPI antibody [EPR7941]; All lanes : Anti-TFPI [EPR7941] antibody at 1/1000 dilution.Lane 1 : HepG2 lysates.Lane 2 : U87-MG lysates.Lane 3 : Caco-2 lysates.Lane 4 : Human placenta lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 35 kDa.