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Anti-TAB3 Antibody EPR5965
Also for TAB3 (NM_152787)
|A synthetic peptide corresponding to residues in human TAB3 was used as an immunogen.|
||Tissue culture supernatant
|Mouse, Human (Does not react with: Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IF
||WB: 1:1000 - 1:10000; ICC/IF: 1:50
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3)|
Entrez Gene 257397 Human
Entrez Gene 66724 Mouse
|TAB3 functions in the NF-kappaB signal transduction pathway. TAB3 and the similar and functionally redundant protein MAP3K7IP2/TAB2, form a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor (1). |
|Druggable Genome NOD-like receptor signaling pathway|
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Western blot - Anti-TAB3 antibody [EPR5965]; All lanes : Anti-TAB3 antibody [EPR5965] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : Caco-2 cell lysate.Lane 5 : RAW264.7 cell lysate.Lane 6 : NIH 3T3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 79 kDa.
Other-Anti-TAB3 antibody [EPR5965](TA310889); Equilibrium disassociation constant (KD)..
Immunocytochemistry - Anti-TAB3 antibody [EPR5965]; TA310889, at 1/50 dilution, staining TAB3 in HepG2 cells by Immunofluorescence.