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Home Antibody All anti-SPHK1 antibodies

Anti-SPHK1 Antibody EPR4293(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310871
  • Rabbit Monoclonal antibody against SPHK1
100ul 325 3-7 Days
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WB(1)
FC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SPHK1 was used as an immunogen.
Clone NameEPR4293(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens sphingosine kinase 1 (SPHK1), transcript variant 3
Alternative NameSPHK
Database LinkNP_001136073
FunctionSphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1. Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor and serum (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - SPHK1 antibody [EPR4293(2)]; All lanes : Anti-SPHK1 antibody [EPR4293(2)] at 1/1000 dilution.Lane 1 : Raji cell lysate.Lane 2 : JAR cell lysate.Lane 3 : HUVEC cell lysate.Lane 4 : HT-1080 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 43 kDa.Observed band size : 51 kDa .</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
FC Image
Flow Cytometry - SPHK1 antibody [EPR4293(2)]; Flow cytometric analysis of permeabilized Raji cells using TA310871 (red), or a rabbit IgG (negative) (green).</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>

 

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