OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
[anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
[SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
[anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
[NPR3] View All Citations >>
Home All anti-SMG5 antibodies
Anti-SMG5 Antibody EPR3503(2)
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
Also for SMG5 (NM_015327)
Homo sapiens smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG5) EST1B; LPTS-RP1; LPTSRP1; RP11-54H19.7; SMG-5 A synthetic peptide corresponding to residues in human SMG5 was used as an immunogen. Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
EPR3503(2)
Human
(Protein A or G Sepharose )
WB, IHC, IF
WB: 1:1,000 - 10,000; IHC 1:50 - 100; FC: 1:10 - 100;
SMG5 is an essential factor in nonsense-mediated mRNA decay, a conserved pathway that degrades mRNAs with premature translation termination codons. Phosphorylated UPF1 is directly recognized by SMG5, SMG6 and SMG7 via a conserved 14-3-3 like domain present in all three proteins. These proteins are thought to serve as adaptors between phosphorylated UPF1 and protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation (1).
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WB Image
Western blot analysis on (A) HeLa, (B) 293T, and (C) K562 cell lysates using anti-SMG5 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-SMG5 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human thyroid gland carcinoma tissue using anti-SMG5 RabMAb.
IF Image
Western blot analysis on (A) HeLa, (B) 293T, and (C) K562 cell lysates using anti-SMG5 RabMAb.
IF Image
Immunofluorescent staining of 293T cells using anti-SMG5 RabMAb.
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