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Home All anti-RRM1 antibodies

Anti-RRM1 Antibody EPR8482

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310828
  • Rabbit Monoclonal antibody against RRM1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC422336) , 20ug
100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IHC(2)
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Also for RRM1 (NM_001033)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens ribonucleotide reductase M1 (RRM1)
Synonyms:R1; RIR1; RR1
ImmunogenA synthetic peptide corresponding to residues in human RRM1 was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR8482 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250;
BackgroundRRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several proteins located in an important tumor-suppressor region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) HeLa, (B) HT-29, (C) RAW 264.7, and (D) NIH/3T3 cell lysates using anti-RRM1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-RRM1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-RRM1 RabMAb.

 

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