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Home Antibody All anti-RRM1 antibodies

Anti-RRM1 Antibody EPR8482

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310828
  • Rabbit Monoclonal antibody against RRM1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC422336) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(2)
Assay(1)
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Also for RRM1 (NM_001033)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human RRM1 was used as an immunogen.
Clone NameEPR8482 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; FC: 1:100 - 1:500
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC/IF or IP.

Reference Data

Target NameHomo sapiens ribonucleotide reductase M1 (RRM1)
Alternative NameR1; RIR1; RR1
Database LinkNP_001024
FunctionRRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several proteins located in an important tumor-suppressor region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-RRM1 antibody [EPR8482]; All lanes : Anti-RRM1 antibody [EPR8482] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HT29 cell lysate .Lane 3 : RAW 264.7 cell lysate.Lane 4 : NIH 3T3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 90 kDa.
Assay Image
Other-Anti-RRM1 antibody [EPR8482](TA310828); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RRM1 antibody [EPR8482]; Immunohistochemical analysis of paraffin-embedded Human placenta tissue labelling RRM1 with TA310828 at 1/250 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RRM1 antibody [EPR8482]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling RRM1 with TA310828 at 1/250 dilution.

 

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