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Anti-RRM1 Antibody EPR8482
Also for RRM1 (NM_001033)
|A synthetic peptide corresponding to residues in human RRM1 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; FC: 1:100 - 1:500
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for ICC/IF or IP.
|Homo sapiens ribonucleotide reductase M1 (RRM1)|
|R1; RIR1; RR1|
|RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several proteins located in an important tumor-suppressor region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer (1). |
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Western blot - Anti-RRM1 antibody [EPR8482]; All lanes : Anti-RRM1 antibody [EPR8482] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HT29 cell lysate .Lane 3 : RAW 264.7 cell lysate.Lane 4 : NIH 3T3 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 90 kDa.
Other-Anti-RRM1 antibody [EPR8482](TA310828); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RRM1 antibody [EPR8482]; Immunohistochemical analysis of paraffin-embedded Human placenta tissue labelling RRM1 with TA310828 at 1/250 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RRM1 antibody [EPR8482]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling RRM1 with TA310828 at 1/250 dilution.