Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
Mutations in the Schizosaccharomyces pombe RAE1 and Saccharomyces cerevisiae Gle2 have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that RAE1 are involved in RNA export. It is a homolog of yeast Rae1. It contains four WD40 motifs and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm.RAE1 is thought to be involved in nucleocytoplasmic transport and directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton (1).
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