Home Antibody All anti-RAB7A antibodies
Anti-RAB7A Antibody EPR7588(B)
Also for RAB7A (NM_004637)
|A synthetic peptide corresponding to residues in human Rab7A was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC: 1:50 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens RAB7A, member RAS oncogene family (RAB7A)|
Entrez Gene 7879 Human
Entrez Gene 29448 Rat
|RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. Rab7A regulates vesicle traffic in late endosomes and also from late endosomes to lysosomes. It is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations in Rab7A have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies (1).|
|Druggable Genome |
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Western blot - Anti-RAB7 antibody [EPR7588(B)]; All lanes : Anti-RAB7 antibody [EPR7588(B)] at 1/1000 dilution.Lane 1 : A375 cell lysate.Lane 2 : A431 cell lysate.Lane 3 : HACAT cell lysate.Lane 4 : Human fetal brain lysate.Lane 5 : B16F0 cell lysate.Lane 6 : C6 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 23 kDa.
Other-Anti-RAB7 antibody [EPR7588(B)](TA310800); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAB7 antibody [EPR7588(B)]; TA310800, at 1/50, staining Rab7A in Paraffin-embedded Human colon adenocarcinoma tissue by Immunohistochemistry.