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Anti-PTPRE Antibody EPR6715
Also for PTPRE (NM_006504)
|A synthetic peptide corresponding to residues in human PTPRE was used as an immunogen|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|71, 75, 81 kDa
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for ICC/IF,IHC-P or IP.
|Homo sapiens protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1|
|HPTPE; PTPE; R-PTP-EPSILON|
Entrez Gene 5791 Human
Entrez Gene 19267 Mouse
Entrez Gene 114767 Rat
|PTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two isoforms have been reported, one of which is a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one is a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar protein in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels (1). |
|TransmembranePhosphataseDruggable Genome |
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Western blot - Anti-PTP epsilon antibody [EPR6715]; All lanes : Anti-PTP epsilon antibody [EPR6715] at 1/1000 dilution.Lane 1 : HL60 cell lysate, treated with TPA.Lane 2 : HL60 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : C2C12 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 71, 75, 81 kDa.
Other-Anti-PTP epsilon antibody [EPR6715](TA310795); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-PTP epsilon antibody [EPR6715]; TA310795 at 1/10 dilution staining PTP epsilon in permeabilized HL60 cells by Flow cytometry (red) compared with a rabbit IgG negative control (green).