Home Antibody All anti-PTPN2 antibodies
Anti-PTPN2 Antibody EPR6712
Also for PTPN2 (NM_080423)
|A synthetic peptide corresponding to residues in human PTPN2 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
|Homo sapiens protein tyrosine phosphatase, non-receptor type 2 (PTPN2), transcript variant 3|
|PTN2; PTPT; TC-PTP; TCELLPTP; TCPTP|
Entrez Gene 5771 Human
Entrez Gene 19255 Mouse
Entrez Gene 117063 Rat
|PTPN2 is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of PTPN2, which suggested its roles in growth factor mediated cell signaling (1).|
|TransmembranePhosphataseDruggable Genome |
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Western blot - Anti-TCPTP antibody [EPR6712]; All lanes : Anti-TCPTP antibody [EPR6712] at 1/1000 dilution.Lane 1 : HL60 cell lysate.Lane 2 : NIH 3T3 cell lysate.Lane 3 : Mouse placenta lysate.Lane 4 : Mouse thymus lysate.Lane 5 : MOLT4 cell lysate.Lane 6 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 48 kDa.Observed band size : 45-48 kDa .