Anti-PPBP Antibody, EPR7767

Also for PPBP (NM_002704)

Gene Name	Homo sapiens pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) (PPBP)
Synonyms:	B-TG1; Beta-TG; CTAP-III; CTAP3; CTAPIII; CXCL7; LA-PF4; LDGF; MDGF; NAP-2; PBP; SCYB7; TC1; TC2;
Immunogen	A synthetic peptide corresponding to residues in human PPBP was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR7767	Isotype
Species Reactivity	Human	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000 - 10,000; ICC: 1:100 - 250;
Background	PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. PPBP also stimulates the formation and secretion of plasminogen activator by synovial cells (1).
Related Pathway	Cytokine-cytokine receptor interaction Hemostasis Signaling by GPCR

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WB Image

Western blot analysis on human platelet lysate using anti-PPBP RabMAb.

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Anti-PPBP Antibody EPR7767

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