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Anti-PMP70 Antibody EPR5614
Also for PMP70 (NM_001122674)
|A synthetic peptide corresponding to residues on the C-terminus in human PMP70 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, Assay, FC
||WB: 1:1000 - 1:10000; ICC: 1:100 - 1:250; FC: 1:100 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for IHC-P or IP.
|Homo sapiens ATP-binding cassette, sub-family D (ALD), member 3 (ABCD3), transcript variant 2|
|ABC43; PMP70; PXMP1; ZWS2|
Entrez Gene 5825 Human
Entrez Gene 19299 Mouse
Entrez Gene 25270 Rat
|PMP70 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). PMP70 is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters, which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations in PMP70 have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders (1).|
|TransmembraneDruggable Genome ABC transporters|
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Western blot - PMP70 antibody [EPR5614]; All lanes : Anti-PMP70 antibody [EPR5614] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : SH SY5Y cell lysate.Lane 3 : Caco2 cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 75 kDa.Observed band size : 70 kDa .
Other-Anti-PMP70 antibody [EPR5614](TA310768); Equilibrium disassociation constant (KD)..
Flow Cytometry - PMP70 antibody [EPR5614]; TA310768 at 1/100 dilution staining PMP70 in permeabilized HepG2 cells by Flow cytometry (shown in red). Rabbit IgG negative control (shown in green).