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Home Antibody All anti-PDX1 antibodies

Anti-PDX1 Antibody EPR3358(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310748
  • Rabbit Monoclonal antibody against PDX1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400074) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(6)
Assay(1)
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Also for PDX1 (NM_000209)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human PDX1 was used as an immunogen.
Clone NameEPR3358(2) IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:1000 - 1:5000; ICC/IF: Use at an assay dependent concentration
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens pancreatic and duodenal homeobox 1 (PDX1)
Alternative NameGSF; IDX-1; IPF1; IUF1; MODY4; PDX-1; STF-1
Database LinkNP_000200
FunctionPDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin expression. Defects in PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of young type 4 (MODY4) (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PDX1 antibody [EPR3358(2)]; All lanes : Anti-PDX1 antibody [EPR3358(2)] at 1/1000 dilution.Lane 1 : CACO-2 cell lysates.Lane 2 : BxPC-3 cell lysates.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 30 kDa.
Assay Image
Other-Anti-PDX1 antibody [EPR3358(2)](TA310748); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDX1 antibody [EPR3358(2)]; Immunohistochemical analysis of paraffin embedded Human pancreas tissue labelled with TA310748 at 1/1000 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDX1 antibody [EPR3358(2)]; Immunohistochemical analysis of paraffin embedded Human duodenum tissue labelled with TA310748 at 1/1000 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDX1 antibody [EPR3358(2)]; TA310748 stainingPDX1 inHuman pancreas tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 5% serum for1 hourat 24°C; antigen retrieval was by heat mediation in10mM sodiumcitrate, pH 6.0. Samples were incubated with primary antibody (1/1000 in2% BSA) for 16 hours at 4°C. An Alexa Fluor? 488-conjugated Donkey anti-rabbit IgG polyclonal (1/400) was used as the secondary antibody.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PDX1 antibody [EPR3358(2)](TA310748); Immunohistochemical analysis of paraffin embedded Human Colonic adenocarcinoma tissue using TA310748 showing +ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PDX1 antibody [EPR3358(2)](TA310748); Immunohistochemical analysis of paraffin embedded Human Heart muscles tissue using TA310748 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PDX1 antibody [EPR3358(2)](TA310748); Immunohistochemical analysis of paraffin embedded normal Human Normal brain tissue using TA310748 showing -ve staining.

 

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