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Home Antibody All anti-OGG1 antibodies

Anti-OGG1 Antibody EPR4664(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310735
  • Rabbit Monoclonal antibody against OGG1
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for OGG1 (NM_002542)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the C-terminus of human OGG1 was used as an immunogen.
Clone NameEPR4664(2) IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens 8-oxoguanine DNA glycosylase (OGG1), transcript variant 1a
Alternative NameHMMH; HOGG1; MUTM; OGH1
Database LinkNP_002533
Entrez Gene 4968 Human
FunctionOGG1 is the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of OGG1 classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization (1).
Related PathwayDruggable Genome Base excision repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Ogg1 antibody [EPR4664(2)]; All lanes : Anti-Ogg1 antibody [EPR4664(2)] at 1/10000 dilution.Lane 1 : Human cerebellum lysate.Lane 2 : HeLa cell lysate.Lane 3 : JAR cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 39 kDa.Observed band size : 39 kDa.
Assay Image
Other-Anti-Ogg1 antibody [EPR4664(2)](TA310735); Equilibrium disassociation constant (KD)..

 

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