Home Antibody All anti-NUDT5 antibodies
Anti-NUDT5 Antibody EPR7734
Also for NUDT5 (NM_014142)
|A synthetic peptide corresponding to residues in human NUDT5 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; FC: 1:100 - 1:500
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for ICC/IF or IP.
|Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 5 (NUDT5)|
|hYSAH1; YSA1; YSA1H; YSAH1|
Entrez Gene 11164 Human
Entrez Gene 53893 Mouse
Entrez Gene 361274 Rat
|Nudix hydrolases, such as NUDT5, eliminate toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites (1). NUDT5 belongs to the Nudix (nucleoside diphosphate linked to another moiety X) hydrolase superfamily of versatile enzymes that are defined by their consensus MutT signature. NUDT5 hydrolyzes 8-oxo-dGDP, 8-oxo-GDP, 8-oxo-dADP, 2-oxo-dADP and 5-CHO-dUDP into their corresponding nucleoside monophosphates and inorganic phosphates. Since 8-oxo-dGDP inhibits hMTH1 activity, the catalytic activity of hNUDT5 also results in the promotion of hMTH1 activity as well as in a reduction in the amount of 8-oxo-dGTP generated from 8-oxo-dGDP by nucleoside diphosphate kinase. Thus, NUDT5 has a role in preventing replicational and transcriptional errors in human cells (2).|
| Purine metabolism|
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Western blot - Anti-NUDT5 antibody [EPR7734]; All lanes : Anti-NUDT5 antibody [EPR7734] at 1/1000 dilution.Lane 1 : U937 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : 293T cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 24 kDa.
Other-Anti-NUDT5 antibody [EPR7734](TA310733); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUDT5 antibody [EPR7734]; TA310733, at a 1/50, staining NUDT5 in paraffin embedded Human kidney tissue by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NUDT5 antibody [EPR7734]; TA310733, at 1/50, staining NUDT5 in paraffin embedded Human bladder carcinoma tissue by Immunohistochemistry.