OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
[anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
[SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
[anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
[NPR3] View All Citations >>
Home All anti-LMAN1 antibodies
Anti-LMAN1 Antibody EPR6979
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
Also for LMAN1 (NM_005570)
Homo sapiens lectin, mannose-binding, 1 (LMAN1) ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60 A synthetic peptide corresponding to residues in human LMAN1 was used as an immunogen. Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
EPR6979
Human, Mouse, Rat
(Protein A or G Sepharose )
WB, IHC
WB: 1:1,000 - 10,000; ICC: 1:100 - 250; IP: 1:10 - 100;
LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. It is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in LMAN1 are associated with a coagulation defect. Using positional cloning, it was identified to lead to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished (1).
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WB Image
Western blot analysis on (A) HeLa, (B) 293T, (C) SH-SY5Y, (D) NCI-H460, (E) Jurkat, and (F) JAR cell lysates using anti-LMAN1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LMAN1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human papillary carcinoma of thyroid gland tissue using anti-LMAN1 RabMAb.
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