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Home Antibody All anti-LMAN1 antibodies

Anti-LMAN1 Antibody EPR6979

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310660
  • Rabbit Monoclonal antibody against LMAN1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401709) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for LMAN1 (NM_005570)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LMAN1 was used as an immunogen.
Clone NameEPR6979 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
Predicted MW Explanation 58 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens lectin, mannose-binding, 1 (LMAN1)
Alternative NameERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60
Database LinkNP_005561
Entrez Gene 3998 Human
Entrez Gene 70361 Mouse
Entrez Gene 116666 Rat
FunctionLMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. It is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in LMAN1 are associated with a coagulation defect. Using positional cloning, it was identified to lead to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished (1).
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-LMAN1 antibody [EPR6979]; All lanes : Anti-LMAN1 antibody [EPR6979] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lane 3 : SH-SY5Y cell lysate.Lane 4 : NCI-H460 cell lysate.Lane 5 : Jurkat cell lysate.Lane 6 : JAR cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 58 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LMAN1 antibody [EPR6979]; TA310660 at 1/100 dilution staining LMAN1 in paraffin-embedded Human kidney tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LMAN1 antibody [EPR6979]; TA310660 at 1/100 dilution staining LMAN1 in paraffin-embedded Human papillary carcinoma of thyroid gland tissue by Immunohistochemistry.

 

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