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Anti-LMAN1 Antibody EPR6979
Also for LMAN1 (NM_005570)
|A synthetic peptide corresponding to residues in human LMAN1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens lectin, mannose-binding, 1 (LMAN1)|
|ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60|
|LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. It is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in LMAN1 are associated with a coagulation defect. Using positional cloning, it was identified to lead to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished (1).|
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Western blot - Anti-LMAN1 antibody [EPR6979]; All lanes : Anti-LMAN1 antibody [EPR6979] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lane 3 : SH-SY5Y cell lysate.Lane 4 : NCI-H460 cell lysate.Lane 5 : Jurkat cell lysate.Lane 6 : JAR cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 58 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LMAN1 antibody [EPR6979]; ab125006 at 1/100 dilution staining LMAN1 in paraffin-embedded Human kidney tissue by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LMAN1 antibody [EPR6979]; ab125006 at 1/100 dilution staining LMAN1 in paraffin-embedded Human papillary carcinoma of thyroid gland tissue by Immunohistochemistry.