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Anti-IGF2R Antibody EPR6599

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(2)

IF(2)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues on the C-terminus of human IGF-2R was used as an immunogen.
Clone Name	EPR6599	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB: 1:50,000 - 200,000; IP: 1:10 - 100; FC: 1:100 - 500;
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens insulin-like growth factor 2 receptor (IGF2R)
Alternative Name	CD222; CIMPR; M6P-R; MPR1; MPRI
Database Link	NP_000867
Function	IGF-2R is a receptor for both insulin-like growth factor 2 (IGF-2) and mannose 6-phosphate (M6P). The IGF-2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, activation of transforming growth factor beta, and degradation of IGF-2. While mouse IGF-2R shows exclusive expression from the maternal allele, imprinting of human IGF-2R appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele (1).
Related Pathway

Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • IGF2R - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • IGF2R - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Igf2r - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • IGF2R - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Igf2r - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens insulin-like growth factor 2 receptor (IGF2R) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens insulin-like growth factor 2 receptor (IGF2R) as transfection-ready DNA Related cDNA Clones • Homo sapiens insulin-like growth factor 2 receptor (IGF2R) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)