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Home Antibody All anti-GSS antibodies

Anti-GSS Antibody EPR6562

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310556
  • Rabbit Monoclonal antibody against GSS
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424876) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GSS was used as an immunogen.
Clone NameEPR6562 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:50 - 1:100; FC: 1:100 - 1:500
Predicted MW Explanation 52 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC/IF or IP.

Reference Data

Target NameHomo sapiens glutathione synthetase (GSS)
Alternative NameGSHS; HEL-S-64p; HEL-S-88n
Database LinkNP_000169
Entrez Gene 2937 Human
Entrez Gene 14854 Mouse
Entrez Gene 25458 Rat
FunctionGlutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. GSS functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in GSS are a cause of glutathione synthetase deficiency (1).
Related PathwayDruggable Genome Glutathione metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Glutathione Synthetase antibody [EPR6562]; All lanes : Anti-Glutathione Synthetase antibody [EPR6562] at 1/10000 dilution.Lane 1 : 293T cell lysates.Lane 2 : HeLa cell lysates.Lane 3 : SW480 cell lysates.Lane 4 : HT 1080 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 52 kDa.Observed band size : 52 kDa.
Assay Image
Other-Anti-Glutathione Synthetase antibody [EPR6562](TA310556); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glutathione Synthetase antibody [EPR6562]; TA310556, at 1/50 dilution staining Glutathione Synthetase in paraffin-embedded Human kidney tissue, by Immunohistochemistry.

 

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