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Anti-GPC3 Antibody EPR5547

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IF(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues in human Glypican-3 was used as an immunogen.
Clone Name	EPR5547	Isotype
Species Reactivity	Human	Concentration
Guaranteed Application *	WB, IF	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250; IP: 1:10 - 100;
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens glypican 3 (GPC3), transcript variant 1
Alternative Name	DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1
Database Link	NP_001158089
Function	Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Glypican-3 can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Mutations in Glypican-3 are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome (1).
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of glypican 3 (GPC3), transcript variant 1 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • GPC3 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • GPC3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Gpc3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • GPC3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Gpc3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens glypican 3 (GPC3), transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human glypican 3 (GPC3), transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human glypican 3 (GPC3), transcript variant 1, mGFP tagged • GFP-tagged ORF clone of Homo sapiens glypican 3 (GPC3), transcript variant 1 as transfection-ready DNA Related cDNA Clones • Homo sapiens glypican 3 (GPC3) transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)