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Anti-GPC3 Antibody EPR5547
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for GPC3 (NM_001164617)
|A synthetic peptide corresponding to residues in human Glypican-3 was used as an immunogen.|
||WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250; IP: 1:10 - 100;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens glypican 3 (GPC3), transcript variant 1|
|DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1|
|Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Glypican-3 can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Mutations in Glypican-3 are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome (1).|
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Western blot analysis on (A) SH-SY5Y, (B) Jurkat, and (C) HepG2 cell lysates using anti-Glypican-3 RabMAb.
Immunofluorescent staining of HepG2 cells using anti-Glypican-3 RabMAb.