Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
G protein alpha 13 belongs to the family of heterotrimeric guanine nucleotide-binding proteins that provide a link between membrane receptors and a set of signaling molecules inside the cell. The alpha-subunit of heterotrimeric G13 proteins regulates multiple cell-type dependent intracellular and cellular events (1). G protein alpha 13 activates Rho through direct stimulation of the guanine nucleotide exchange factor p115RhoGEF. Like all G-proteins, Rho cycles between the inactive GDP bound and active GTP bound form (2).
Related Pathway
Hemostasis
Signaling by GPCR
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