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Home Antibody All anti-GLA antibodies

Anti-GLA Antibody EPR5829

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310535
  • Rabbit Monoclonal antibody against GLA
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400067) , 20ug
100ul 325 In Stock
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WB(1)
FC(1)
Assay(1)
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Also for GLA (NM_000169)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the C-terminus of human GLA was used as an immunogen.
Clone NameEPR5829 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:100 - 1:500
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens galactosidase, alpha (GLA)
Alternative NameGALA
Database LinkNP_000160
FunctionGLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this GLA affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties (1).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Galactosidase alpha antibody [EPR5829]; All lanes : Anti-Galactosidase alpha antibody [EPR5829] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : A431 cell lysate.Lane 3 : MCF7 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 49 kDa.
Assay Image
Other-Anti-Galactosidase alpha antibody [EPR5829](TA310535); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-Galactosidase alpha antibody [EPR5829]; TA310535 (red), at a 1/100 dilution, staining Galactosidase alpha in permeabilized MCF7 cells by Flow Cytometry. A rabbit IgG was used as a negative control (green).

 

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