Anti-FTO Antibody, EPR6895

Also for FTO (NM_001080432)

Gene Name	Homo sapiens fat mass and obesity associated (FTO)
Synonyms:	KIAA1752; MGC5149
Immunogen	A synthetic peptide corresponding to residues in human FTO was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR6895	Isotype
Species Reactivity	Human	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:10,000 - 50,000; IHC 1:100 - 250; ICC: 1:250 - 500; IP: 1:10 - 100; FC: 1:10 - 100;
Background	The exact function of FTO is not known. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Studies of type 2 diabetes indicate FTO is related to diabetes susceptibility. Mutation in this protein has been associated with growth retardation, developmental delay, coarse facies, and early death (1).
Related Pathway

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WB Image

Western blot analysis on (A) 293T, (B) SH-SY5Y, (C) Caco-2, and (D) BxPC-3 cell lysates using anti-FTO RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-FTO RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-FTO RabMAb.

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Anti-FTO Antibody EPR6895

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