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Home Antibody All anti-FOSL2 antibodies

Anti-FOSL2 Antibody EPR4713(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310497
  • Rabbit Monoclonal antibody against Fra-2 (FOSL2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417421) , 20ug
100ul 325 In Stock
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WB(1)
FC(1)
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Also for FOSL2 (NM_005253)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human Fra-2 was used as an immunogen.
Clone NameEPR4713(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:100 - 1:500
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IHC-P.

Reference Data

Target NameHomo sapiens FOS-like antigen 2 (FOSL2)
Alternative NameFRA2
Database LinkNP_005244
FunctionFra-2, one of the Fos-related antigens, is promptly expressed after the growth stimulation of fibroblasts, but its induction peak is later than that of c-Fos (1). Fra-2 belongs to the activator protein 1 family of transcription factors, and it regulates the production of extracellular matrix in systemic sclerosis (SSc). It has been demonstrated that Fra-2 is overexpressed in SSc and acts as a novel downstream mediator of the profibrotic effects of TGFß and PDGF. It might be an interesting novel candidate for molecular-targeted therapies for SSc (2).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-FRA2 antibody [EPR4713(2)]; All lanes : Anti-FRA2 antibody [EPR4713(2)] at 1/1000 dilution.Lane 1 : MCF7 cell lysate.Lane 2 : F9 cell lysate.Lane 3 : PC12 cell lysate.Lane 4 : NCCIT cell lysate.Lane 5 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 35 kDa.
FC Image
Flow Cytometry - Anti-FRA2 antibody [EPR4713(2)]; TA310497 at 1/100 dilution staining FRA2 in permeabilized 293T cells (red). A rabbit IgG was used as negative control (green).

 

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