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Anti-FBP2 Antibody EPR7436


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against FBP2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418397) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human FBP2 was used as an immunogen.
Clone NameEPR7436 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
Predicted MW Explanation 37 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens fructose-1,6-bisphosphatase 2 (FBP2)
Alternative NameMGC142192
Database LinkNP_003828
Entrez Gene 8789 Human
Entrez Gene 14120 Mouse
Entrez Gene 114508 Rat
FunctionFBP2, also known as Fructose-1,6-bisphosphatase isozyme 2, belongs to the FBPase class 1 family (1). It is a gluconeogenesis regulatory enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate (2). FBP2 is subject to complex allosteric regulation. The enzyme can assume an active R-state, or an inactive T-state. Intermediate conformations may exist. AMP acts as allosteric inhibitor. Fructose-2,6-biphosphate acts as competitive inhibitor (1).
Related PathwayDruggable Genome Glycolysis / GluconeogenesisPentose phosphate pathwayFructose and mannose metabolismMetabolic pathwaysInsulin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-FBP2 antibody [EPR7436]; All lanes : Anti-FBP2 antibody [EPR7436] at 1/1000 dilution.Lane 1 : Human skeletal muscle lysate.Lane 2 : Rat muscle lysate.Lane 3 : Mouse muscle lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti Rabbit IgG at 1/2000 dilution.Predicted band size : 37 kDa.
Other-Anti-FBP2 antibody [EPR7436](TA310483); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FBP2 antibody [EPR7436]; Immunohistochemical analysis of paraffin embedded Human muscle tissue labelling FBP2 with TA310483 antibody at 1/50 dilution.


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