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Anti-DSG1 Antibody EPR6766(B)
Also for DSG1 (NM_001942)
|A synthetic peptide corresponding to residues at the C-terminus of human DSG1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for ICC or IP.
|Homo sapiens desmoglein 1 (DSG1)|
|CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1|
|Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. DSG1 (Desmoglein 1) is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. DSG1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus (1). |
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Western blot - Anti-Desmoglein 1 antibody [EPR6766(B)]; Anti-Desmoglein 1 antibody [EPR6766(B)] at 1/1000 dilution + Human skin lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 114 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Desmoglein 1 antibody [EPR6766(B)]; TA310426, at a 1/250 dilution, staining Desmoglein 1 in paraffin embedded Human skin tissue by Immunohistochemistry.