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Home Antibody All anti-DOCK2 antibodies

Anti-DOCK2 Antibody EPR6647

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310415
  • Rabbit Monoclonal antibody against DOCK2
100ul $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human DOCK2 was used as an immunogen.
Clone NameEPR6647 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens dedicator of cytokinesis 2 (DOCK2)
Alternative NameFLJ46592; KIAA0209
Database LinkNP_004937
FunctionDOCK2 is a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis (1). DOCK2 plays a critical role in lymphocyte homing and immunological synapse formation by regulating the actin cytoskeleton. It has been shown that DOCK2 deficiency enables long-term survival of cardiac allografts across a complete mismatch of the major histocompatibility complex molecules. DOCK2 is critical for CD28-mediated Rac activation and is required for the full activation of alloreactive T cells (2).
Related Pathway

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WB Image
Western blot - Anti-DOCK2 antibody [EPR6647]; All lanes : Anti-DOCK2 antibody [EPR6647] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : Raji cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 212 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DOCK2 antibody [EPR6647]; TA310415, at 1/50 - 1/100, staining DOCK2 in Human lung tissue by immunohistochemistry [Paraffin Embedded Tissues (IHC-P)].

 

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