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Anti-DMRT1 Antibody EPR6936
Also for DMRT1 (NM_021951)
|A synthetic peptide corresponding to residues near the N-terminus of human DMRT1 was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:100 - 1:500
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IHC-P.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens doublesex and mab-3 related transcription factor 1 (DMRT1)|
|DMRT1 is found in a cluster with two other members of the protein family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. DMRT1 exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when DMRT1 is hemizygous (1). |
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Western blot - Anti-DMRT1 antibody [EPR6936]; All lanes : Anti-DMRT1 antibody [EPR6936] at 1/1000 dilution.Lane 1 : Human testis lysate.Lane 2 : HL-60 lysate.Lane 3 : Human seminoma lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 39 kDa.Observed band size : 34 kDa .