Anti-DCTN2 Antibody, EPR5094

Also for DCTN2 (NM_001261412)

Gene Name	Homo sapiens dynactin 2 (p50) (DCTN2), transcript variant 2
Synonyms:	DCTN50; DYNAMITIN; RBP50
Immunogen	A synthetic peptide corresponding to residues in human DCTN2 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR5094	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, FC	Suggested Dilutions	WB: 1:10,000-50,000; FC: 1:100 - 500;
Background	DCTN2 is a subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. DCTN2 contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Related Pathway	Cell cycle

* Shipping is in business days

* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

Western blot analysis on (A) MCF-7, (B) A375, (C) Saos-2, and (D) SH-SY5Y cell lysates using anti-DCTN2 RabMAb.

FC Image

Flow cytometric analysis of permeabilized Saos-2 cells using anti-DCTN2 RabMAb (red) or a rabbit IgG (negative) (green).

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

OriGene Antibodies in recent publications

Anti-DCTN2 Antibody EPR5094

TrueMAB™ Antibodies - Made against Authentic Protein Antigens