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Home Antibody All anti-DCTN2 antibodies

Anti-DCTN2 Antibody EPR5094

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310397
  • Rabbit Monoclonal antibody against DCTN2
100ul 325 3-7 Days
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WB(1)
FC(1)
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Also for DCTN2 (NM_006400)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DCTN2 was used as an immunogen.
Clone NameEPR5094 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
Predicted MW Explanation 44 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IHC-P.

Reference Data

Target NameHomo sapiens dynactin 2 (p50) (DCTN2), transcript variant 1
Alternative NameDCTN50; DYNAMITIN; HEL-S-77; RBP50
Database LinkNP_006391
Entrez Gene 10540 Human
Entrez Gene 69654 Mouse
Entrez Gene 299850 Rat
FunctionDCTN2 is a subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. DCTN2 contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Related Pathway Huntington's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Dynamitin antibody [EPR5094]; All lanes : Anti-Dynamitin antibody [EPR5094] at 1/10000 dilution.Lane 1 : MCF7 cell lysate.Lane 2 : A375 cell lysate.Lane 3 : Saos2 cell lysate.Lane 4 : SH Y5Y cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 44 kDa.
FC Image
Flow Cytometry - Dynamitin antibody [EPR5094]; TA310397 at 1/10 dilution staining Dynamitin in Saos2 cells by Flow cytometry (red) or a rabbit IgG (negative) (green).

 

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