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Home Antibody All anti-DCAMKL1 antibodies

Anti-DCAMKL1 Antibody EPR6085


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against DCAMKL1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417785) , 20ug Explanation
100ul $325 3-7 Days
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Also for DCAMKL1 (NM_004734)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DCAMKL1 was used as an immunogen.
Clone NameEPR6085 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC: 1:100 - 1:250
Predicted MW Explanation 82 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens doublecortin-like kinase 1 (DCLK1), transcript variant 1
Alternative NameCL1; CLICK1; DCAMKL1; DCDC3A; DCLK
Database LinkNP_004725
Entrez Gene 9201 Human
Entrez Gene 13175 Mouse
Entrez Gene 83825 Rat
FunctionDCAMKL1 is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinases, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of DCAMKL1 is independent of its protein kinase activity. It is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. Furthermore, DCAMKL1 is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities (1).
Related PathwayProtein KinaseDruggable Genome

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - DCAMKL1 antibody [EPR6085]; All lanes : Anti-DCAMKL1 antibody [EPR6085] at 1/1000 dilution.Lane 1 : Human fetal lung lysate.Lane 2 : NIH3T3 lysate.Lane 3 : SH-SY5Y lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 82 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DCAMKL1 antibody [EPR6085]; Immunohistochemical analysis of paraffin-embedded Human brain tissue using TA310395 at a dilution of 1/100.


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