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Anti-DBF4 Antibody EPR5635


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against DBF4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402007) , 20ug Explanation
100ul 325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DBF4 was used as an immunogen.
Clone NameEPR5635 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens DBF4 zinc finger (DBF4)
Alternative NameASK; CHIF; DBF4A; ZDBF1
Database LinkNP_006707
Entrez Gene 10926 Human
FunctionDBF4 is a regulatory protein that is required for Cdc7 kinase activation and forms a stable two-subunit complex with Cdc7. A two-subunit serine/threonine kinase, Cdc7-DBF4, is required for initiating DNA replication in all eukaryotes. Cdc7 is expressed at constant levels during the cell cycle, but DBF4 levels are cyclical and peak near the G1/S phase transition. Cdc7-DBF4 is recruited to replication origins to promote DNA synthesis by activating the MCM helicase (1).
Related PathwayDruggable Genome Cell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-DBF4 antibody [EPR5635]; All lanes : Anti-DBF4 antibody [EPR5635] at 1/10000 dilution.Lane 1 : PC-3 cell lysates.Lane 2 : Jurkat cell lysates.Lane 3 : SW480 cell lysates.Lane 4 : HepG2 cell lysates.Lysates/proteins at 10 ug per lane.Predicted band size : 77 kDa.
Assay Image
Other-Anti-DBF4 antibody [EPR5635](TA310394); Equilibrium disassociation constant (KD)..


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