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Home Antibody All anti-CST3 antibodies

Anti-CST3 Antibody EPR4413

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310364
  • Rabbit Monoclonal antibody against Cystatin C (CST3)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400040) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for CST3 (NM_000099)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA recombinant protein fragment corresponding to residues in human Cystatin C was used as an immunogen.
Clone NameEPR4413 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens cystatin C (CST3), transcript variant 1
Alternative NameARMD11
Database LinkNP_000090
FunctionThe cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. Cystatin C is the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease (1).
Related Pathway

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WB Image
Western blot - Cystatin C antibody [EPR4413]; All lanes : Anti-Cystatin C antibody [EPR4413] at 1/10000 dilution.Lane 1 : Human testis lysate.Lane 2 : HeLa testis lysate.Lane 3 : HepG2 testis lysate.Lane 4 : U87-MG testis lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 15 kDa.Observed band size : 13 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cystatin C antibody [EPR4413]; Immunohistochemical analysis of paraffin-embedded Human brain tissue using TA310364 at adilution of 1/250.

 

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