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Anti-CST3 Antibody EPR4413
Also for CST3 (NM_000099)
|A recombinant protein fragment corresponding to residues in human Cystatin C was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000; IHC-P: 1:250 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens cystatin C (CST3), transcript variant 1|
|The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. Cystatin C is the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease (1).|
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Western blot - Cystatin C antibody [EPR4413]; All lanes : Anti-Cystatin C antibody [EPR4413] at 1/10000 dilution.Lane 1 : Human testis lysate.Lane 2 : HeLa testis lysate.Lane 3 : HepG2 testis lysate.Lane 4 : U87-MG testis lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 15 kDa.Observed band size : 13 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cystatin C antibody [EPR4413]; Immunohistochemical analysis of paraffin-embedded Human brain tissue using TA310364 at adilution of 1/250.