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Anti-COPS5 Antibody EPR1350
Also for COPS5 (NM_006837)
|A synthetic peptide corresponding to residues in human COPS5 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC/IF: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt.
|Homo sapiens COP9 signalosome subunit 5 (COPS5)|
|CSN5; JAB1; MOV-34; SGN5|
|COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. COPS5 is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors (1).|
TGF Beta Signaling Pathway
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Western blot - Anti-JAB1 antibody [EPR1350]; All lanes : Anti-JAB1 antibody [EPR1350] at 1/1000 dilution.Lane 1 : NIH 3T3 cell lysate.Lane 2 : U87-MG cell lysate.Lane 3 : MCF7 cell lysate.Lane 4 : PC12 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 38 kDa.
Other-Anti-JAB1 antibody [EPR1350](ab124720); Equilibrium disassociation constant (KD)..