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Home Antibody All anti-CD25 antibodies

Anti-CD25 Antibody EPR6452

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA310265 Rabbit Monoclonal antibody against CD25 100ul $325 In Stock
LC424732 IL2RA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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IHC(5)
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OriGene Data

ImmunogenA recombinant protein fragment corresponding to human CD25 was used as an immunogen.
Clone NameEPR6452 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *IHC Suggested DilutionsIHC-P 1:250 - 1:500; ICC 1:100-1:250
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat; Is unsuitable for IP

Reference Data

Target NameHomo sapiens interleukin 2 receptor, alpha (IL2RA), transcript variant 1
Alternative NameCD25; IDDM10; IL2R; p55; TCGFR
Database LinkNP_000408
Entrez Gene 3559 Human
FunctionCD25, or interleukin 2 (IL2) receptor alpha (IL2RA), and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (CD25) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble CD25 has been isolated and determined to result from extracellular proteolyisis. Mutations in CD25 are associated with interleukin 2 receptor alpha deficiency (1).
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Cytokine-cytokine receptor interactionEndocytosisJak-STAT signaling pathwayHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL2 Receptor alpha antibody [EPR6452]; TA310265, at 1/250 dilution, staining IL2 Receptor alpha in paraffin-embedded Human tonsil tissue by Immunohistochemistry.
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IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL2 Receptor alpha antibody [EPR6452](TA310265); TA310265 showing positive staining in Hodgkin's lymphoma tissue.
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IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL2 Receptor alpha antibody [EPR6452](TA310265); TA310265 showing negative staining in Normal liver tissue.
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IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL2 Receptor alpha antibody [EPR6452](TA310265); TA310265 showing positive staining in Normal thymus tissue.
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IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL2 Receptor alpha antibody [EPR6452](TA310265); TA310265 showing positive staining in Normal spleen tissue.
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