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Home Antibody All anti-CBS antibodies

Anti-CBS Antibody EPR8578

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310246
  • Rabbit Monoclonal antibody against CBS
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400017) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human CBS was used as an immunogen.
Clone NameEPR8578 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens cystathionine-beta-synthase (CBS), transcript variant 1
Alternative NameHIP4
Database LinkNP_000062
Entrez Gene 875 Human
FunctionCBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. It is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in CBS can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria (1).
Related PathwayDruggable Genome Glycine, serine and threonine metabolismCysteine and methionine metabolismSelenoamino acid metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-CBS antibody [EPR8578]; All lanes : Anti-CBS antibody [EPR8578] at 1/1000 dilution.Lane 1 : Fetal liver lysate.Lane 2 : Raji cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 61 kDa.
Assay Image
Other-Anti-CBS antibody [EPR8578](TA310246); Equilibrium disassociation constant (KD)..

 

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