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Anti-CBS Antibody EPR8578
|A synthetic peptide corresponding to residues near the N-terminus of human CBS was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens cystathionine-beta-synthase (CBS), transcript variant 1|
|CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. It is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in CBS can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria (1). |
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Western blot - Anti-CBS antibody [EPR8578]; All lanes : Anti-CBS antibody [EPR8578] at 1/1000 dilution.Lane 1 : Fetal liver lysate.Lane 2 : Raji cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 61 kDa.
Other-Anti-CBS antibody [EPR8578](ab131155); Equilibrium disassociation constant (KD)..