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Anti-CARD9 Antibody EPR6489
Also for CARD9 (NM_052813)
|A synthetic peptide corresponding to residues in human CARD9 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for ICC/IF,IHC-P or IP.
|Homo sapiens caspase recruitment domain family, member 9 (CARD9), transcript variant 1|
Entrez Gene 64170 Human
|CARD9 is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. CARD9 was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB (1). |
|Druggable Genome NOD-like receptor signaling pathway|
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Western blot - Anti-CARD9 antibody [EPR6489 ]; All lanes : Anti-CARD9 antibody [EPR6489 ] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : U937 cell lysate.Lane 3 : HL60 cell lysate.Lane 4 : HepG2 cell lysate.Lane 5 : THP1 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 62 kDa.
Other-Anti-CARD9 antibody [EPR6489 ](TA310234); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-CARD9 antibody [EPR6489 ]; Flow Cytometric analysis of permeabilized HL60 cells labelling CARD9 with TA310234 at a dilution of 1/10 (red) or a rabbit IgG (negative) (green).