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Home Antibody All anti-ACTL6A antibodies

Anti-ACTL6A Antibody EPR7443

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310170
  • Rabbit Monoclonal antibody against BAF53 (ACTL6A)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418091) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for ACTL6A (NM_004301)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human BAF53 was used as an immunogen.
Clone NameEPR7443 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; ICC/IF: 1:100 - 1:250
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens actin-like 6A (ACTL6A), transcript variant 1
Alternative NameACTL6; Arp4; ARPN-BETA; BAF53A; INO80K
Database LinkNP_004292
FunctionBAF53 is a family member of actin-related proteins (ARPs) that share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. BAF53 is a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate activation of specific proteins by antagonizing chromatin-mediated repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1 and the association of the BAF complex with chromatin/matrix (1).
Related Pathway

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WB Image
Western blot - Anti-ACTL6A antibody [EPR7443]; All lanes : Anti-ACTL6A antibody [EPR7443] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : K562 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled Goat anti-Rabbit IgG at 1/2000 dilution.Predicted band size : 47 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACTL6A antibody [EPR7443]; Immunohistochemical analysis of paraffin embedded Human breast carcinoma tissue labelling ACTL6A with TA310170 at 1/50 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACTL6A antibody [EPR7443]; Immunohistochemical analysis of paraffin embedded Human colon tissue labelling ACTL6A with TA310170 at 1/50 dilution.

 

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