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Anti-ABCG5 Antibody EPR6203
Also for ABCG5 (NM_022436)
|A synthetic peptide corresponding to residues in human ABCG5 was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
|Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 5 (ABCG5)|
Entrez Gene 64240 Human
|ABCG5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCG5 is a member of the White subfamily. It functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. ABCG5 is expressed in a tissue-specific manner in the liver, colon, and intestine. Mutations in this protein may contribute to sterol accumulation and atheroschlerosis, and they have been observed in patients with sitosterolemia (1). |
|TransmembraneDruggable Genome ABC transporters|
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Western blot - Anti-ABCG5 antibody [EPR6203]; All lanes : Anti-ABCG5 antibody [EPR6203] at 1/1000 dilution.Lane 1 : Ramos cell lysates.Lane 2 : HepG2 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 72 kDa.
Other-Anti-ABCG5 antibody [EPR6203](TA310164); Equilibrium disassociation constant (KD)..